Welcome to DINC 2.0!

DINC is a parallelized meta-docking method for the incremental docking of large ligands (currently using AutoDock 4)

A small molecule (such as a drug or a peptide) in a .pdb file

A protein (ideally, without ions) in a .pdb file

Center of the bounding box containing the binding site

Be sure to place the grid center near the receptor's surface; X, Y, Z should be given in Å

Dimensions of the bounding box (defining the ligand's search space)

X, Y, Z define the number of grid points in each dimension; grid point spacing is 0.375 Å X, Y, Z should be even integers between 10 and 126

The dimensions of the bounding box are now:

Å × Å × Å

Your email address will only be used to send you a link to the docking results

Select a number between 5 and 10

Select a number between 10 and 50

Select a number between 100 and 300

Increasing the values of these parameters can improve the likelihood of obtaining good predictions, but can increase running time

Privacy policy

Data and results of each user are not accessible to other users, but we cannot guarantee full privacy. We assume the data submitted to DINC is not strictly confidential.

Data retention policy

Data and results will be stored on the server only for a limited amount of time. The content of the server will be periodically deleted.